Coral Barbas

Principal investigator

Coral Barbas

Coral Barbas

Web of Science ResearcherID: https://www.webofscience.com/wos/author/record/1615126
Bio: Coral Barbas Arribas is currently Full Professor of Analytical Chemistry at the Chemistry and Biochemistry Department of the Faculty of Pharmacy at Universidad CEU San Pablo, Madrid (Spain) and Director of the “Centre for Metabolomics and Bioanalysis” (CEMBIO) at this Faculty. She is also Director of CEU International School of Doctorate (CEINDO); Visiting Professor at Imperial College London, Department of Surgery and Cancer and at Bialystok Medical University. As previous appointments, she was Vice-Chancellor for Research at Universidad CEU San Pablo and Marie Curie Fellow at Kings College London. She is the author of more than 200 publications and book chapters, with current research interests in all the steps in metabolomics workflow: experimental design, sample pretreatment, analytical methods for targeted and untargeted metabolomics focused on multiplatform analysis with GC-MS, LC-MS and CE-MS, method validation, data treatment, compound identification and interpretation. Main awards: Honoris Causa Doctorate at Bialystok Medical University, Medal of the Belgian Society of Pharmaceutical Sciences. She is currently president of the new board of the Royal Spanish Chemistry Society in the territorial section of Madrid.
Web of Science ResearcherID: K-3871-2014
ORCID: 0000-0003-4722-491X

Publications by Coral Barbas:

Neurons regulate the esterification of bioactive lipid mediators in the brain of acid sphingomyelinase deficient mice

Posted on: 08 Feb 2024

GC-MS-based metabolomics of volatile organic compounds in exhaled breath: applications in health and disease. A review

Posted on: 08 Ene 2024

LiLA: lipid lung-based ATLAS built through a comprehensive workflow designed for an accurate lipid annotation

Posted on: 05 Ene 2024

Identifying subgroups of childhood obesity by using multiplatform metabotyping

Posted on: 20 Dic 2023

Application of a capillary electrophoresis–mass spectrometry metabolomics workflow in zebrafish larvae reveals new effects of cortisol

Posted on: 10 Dic 2023

Metabolomic profile of neuroendocrine tumors identifies methionine, porphyrin, and tryptophan metabolisms as key dysregulated pathways associated with patient survival

Posted on: 30 Nov 2023

Differential abundance of lipids and metabolites related to SARS-CoV-2 infection and susceptibility

Posted on: 13 Sep 2023

Platelet-Derived Extracellular Vesicles as Lipid Carriers in Severe Allergic Inflammation

Posted on: 12 Ago 2023

Reciprocal regulation between the molecular clock and kidney injury

Posted on: 24 Jul 2023

Metabolic profiling of Alzheimer’s disease: Untargeted metabolomics analysis of plasma samples

Posted on: 16 Jul 2023

IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype

Posted on: 12 Jul 2023

Multiplatform Metabolomics Characterization Reveals Novel Metabolites and Phospholipid Compositional Rules of Haemophilus influenzae Rd KW20

Posted on: 06 Jul 2023

Growth hormone remodels the 3D-structure of the mitochondria of inflammatory macrophages and promotes metabolic reprogramming

Posted on: 05 Jul 2023

Leishmania donovani Induces Multiple Dynamic Responses in the Metabolome Associated with Amastigote Differentiation and Maturation Inside the Human Macrophage

Posted on: 20 Jun 2023

Impact of renal tubular Cpt1a overexpression on the kidney metabolome in the folic acid-induced fibrosis mouse model

Posted on: 12 Jun 2023

γ-Linolenic acid in maternal milk drives cardiac metabolic maturation

Posted on: 24 May 2023

A host-specific diaminobutyrate aminotransferase contributes to symbiotic performance, homoserine metabolism, and competitiveness in the Rhizobium leguminosarum/Pisum sativum system

Posted on: 16 May 2023

Mapping early serum proteome signatures of liver regeneration in living donor liver transplant cases

Posted on: 12 May 2023

The role of oxylipins and their validation as biomarkers in the clinical context

Posted on: 24 Abr 2023

Capillary electrophoresis mass spectrometry-based untargeted metabolomics to approach disease diagnosis

Posted on: 02 Abr 2023

Integrating the potential of ion mobility spectrometry-mass spectrometry in the separation and structural characterisation of lipid isomers

Posted on: 16 Mar 2023

Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis

Posted on: 23 Feb 2023

Deciphering the role of platelets in severe allergy by an integrative omics approach

Posted on: 17 Dic 2022

Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus

Posted on: 08 Dic 2022

Genomics, Transcriptomics, and Metabolomics Reveal That Minimal Modifications in the Host Are Crucial for the Compensatory Evolution of ColE1-Like Plasmids

Posted on: 23 Nov 2022

Optimization of sample extraction and injection-related parameters in HILIC performance for polar metabolite analysis. Application to the study of a model of pulmonary hypertension

Posted on: 30 Oct 2022

Strategies for Identification of Modified Amino Acids with CE–MS in Metabolomics

Posted on: 07 Oct 2022

Contribution of allergy in the acquisition of uncontrolled severe asthma

Posted on: 21 Sep 2022

Birth Weight and Early Postnatal Outcomes: Association with the Cord Blood Lipidome

Posted on: 12 Sep 2022

Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR)

Posted on: 06 Sep 2022

Ligand diversity contributes to the full activation of the jasmonate pathway in Marchantia polymorpha

Posted on: 29 Ago 2022

Optimization of capillary electrophoresis coupled to negative mode electrospray ionization-mass spectrometry using polyvinyl alcohol coated capillaries. Application to a study on non-small cell lung cancer

Posted on: 17 Ago 2022

In-Source Fragmentation for the Identification of Compounds by CE-ESI-TOF in Human Plasma. L-Proline as Case Study

Posted on: 09 Ago 2022

Molecular signature of renal cell carcinoma by means of a multiplatform metabolomics analysis

Posted on: 04 Ago 2022

Plasma lipidomics in subjects with combat posttraumatic stress disorder

Posted on: 31 Jul 2022

Sphingomyelin Depletion Inhibits CXCR4 Dynamics and CXCL12-Mediated Directed Cell Migration in Human T Cells

Posted on: 12 Jul 2022

Energy metabolism as a target for cyclobenzaprine: A drug candidate against Visceral Leishmaniasis

Posted on: 06 Jul 2022

Metabolic Profiling at COVID-19 Onset Shows Disease Severity and Sex-Specific Dysregulation

Posted on: 30 Jun 2022

Untargeted Metabolomics Studies of H9c2 Cardiac Cells Submitted to Oxidative Stress, β-Adrenergic Stimulation and Doxorubicin Treatment: Investigation of Cardiac Biomarkers

Posted on: 29 Jun 2022

Development of a Novel Targeted Metabolomic LC-QqQ-MS Method in Allergic Inflammation

Posted on: 25 Jun 2022

Omics technologies in allergy and asthma research: An EAACI position paper

Posted on: 17 Jun 2022

Probabilistic metabolite annotation using retention time prediction and meta-learned projections

Posted on: 07 Jun 2022

Recent developments in data acquisition, treatment and analysis with ion mobility-mass spectrometry for lipidomics

Posted on: 02 Jun 2022

A Set of Reliable Samples for the Study of Biomarkers for the Early Diagnosis of Parkinson’s Disease

Posted on: 30 May 2022

New molecular mechanisms in cholangiocarcinoma: signals triggering interleukin-6 production in tumor cells and KRAS co-opted epigenetic mediators driving metabolic reprogramming

Posted on: 26 May 2022

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist

Posted on: 07 Mar 2022

Metabolomics and biochemical alterations caused by pleiotrophin in the 6-hydroxydopamine mouse model of Parkinson’s disease

Posted on: 04 Mar 2022

Metabolic Modeling in Health and Disease

Posted on: 04 Mar 2022

Targeting the Gut Microbiota of Vertically HIV-Infected Children to Decrease Inflammation and Immunoactivation: A Pilot Clinical Trial

Posted on: 26 Feb 2022

Metabolic Snapshot of Plasma Samples Reveals New Pathways Implicated in SARS-CoV-2 Pathogenesis

Posted on: 08 Feb 2022

Ceramide Composition in Exosomes for Characterization of Glioblastoma Stem-Like Cell Phenotypes

Posted on: 21 Ene 2022

Metabolomic changes after DAAs therapy are related to the improvement of cirrhosis and inflammation in HIV/HCV-coinfected patients

Posted on: 12 Ene 2022

Metformin Treatment or PRODH/POX-Knock out Similarly Induces Apoptosis by Reprogramming of Amino Acid Metabolism, TCA, Urea Cycle and Pentose Phosphate Pathway in MCF-7 Breast Cancer Cells

Posted on: 15 Dic 2021

Blood microbiome is associated with changes in portal hypertension after successful direct-acting antiviral therapy in patients with HCV-related cirrhosis

Posted on: 09 Dic 2021

An evolutionarily ancient fatty acid desaturase is required for the synthesis of hexadecatrienoic acid, which is the main source of the bioactive jasmonate in Marchantia polymorpha

Posted on: 30 Nov 2021

Understanding uncontrolled severe allergic asthma by integration of omic and clinical data

Posted on: 28 Nov 2021

Unveiling Metabolic Phenotype Alterations in Anorexia Nervosa through Metabolomics

Posted on: 26 Nov 2021

Gas Chromatography–Mass Spectroscopy-Based Metabolomics Analysis Reveals Potential Biochemical Markers for Diagnosis of Gestational Diabetes Mellitus

Posted on: 19 Nov 2021

Exploiting the formation of adducts in mobile phases with ammonium fluoride for the enhancement of annotation in liquid chromatography-high resolution mass spectrometry based lipidomics

Posted on: 05 Nov 2021

Characterization of anaphylaxis reveals different metabolic changes depending on severity and triggers

Posted on: 29 Oct 2021

Analytical approaches for studying oxygenated lipids in the search of potential biomarkers by LC-MS

Posted on: 01 Oct 2021

Comparative metabolomics analysis of bronchial epithelium during barrier establishment after allergen exposure

Posted on: 21 Sep 2021

Low and high resolution gas chromatography-mass spectrometry for untargeted metabolomics: A tutorial

Posted on: 09 Sep 2021

In vitro generation of oxidized standards for lipidomics. Application to major membrane lipid components

Posted on: 16 Ago 2021

Integration of Functional Genomic, Transcriptomic, and Metabolomic Data to Identify Key Features in Genomic Expression, Metabolites, and Metabolic Pathways of Babesia divergens

Posted on: 30 Jul 2021

A Preliminary Study Showing the Impact of Genetic and Dietary Factors on GC–MS-Based Plasma Metabolome of Patients with and without PROX1-Genetic Predisposition to T2DM up to 5 Years Prior to Prediabetes Appearance

Posted on: 29 Jun 2021

Metabolomic Reprogramming of C57BL/6-Macrophages during Early Infection with L. amazonensis

Posted on: 26 Jun 2021

Metabolomics reveals synergy between Ag and g-C3N4 in Ag/gC3N4 composite photocatalysts: a unique feature among Ag-doped biocidal materials

Posted on: 01 Jun 2021

Comprehensive Plasma Metabolomic Profile of Patients with Advanced Neuroendocrine Tumors (NETs). Diagnostic and Biological Relevance

Posted on: 27 May 2021

Aspergillus Metabolome Database for Mass Spectrometry Metabolomics

Posted on: 15 May 2021

Understanding Systemic and Local Inflammation Induced by Nasal Polyposis: Role of the Allergic Phenotype

Posted on: 14 May 2021

Noninvasive monitoring of evolving urinary metabolic patterns in neonatal encephalopathy

Posted on: 05 May 2021

Combined Genome, Transcriptome and Metabolome Analysis in the Diagnosis of Childhood Cerebellar Ataxia

Posted on: 15 Mar 2021

Searching for prognostic biomarkers of Parkinson’s Disease development in the Spanish EPIC cohort through a multiplatform metabolomics approach

Posted on: 03 Mar 2021

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

Posted on: 19 Ene 2021

Enhancing confidence of metabolite annotation in Capillary Electrophoresis-Mass Spectrometry untargeted metabolomics with relative migration time and in-source fragmentation

Posted on: 04 Ene 2021

Utilization of low molecular weight organic compounds by the filterable fraction of a lotic microbiome

Posted on: 02 Dic 2020

Sample pre-treatment procedures for the omics analysis of human gut microbiota: Turning points, tips and tricks for gene sequencing and metabolomics

Posted on: 30 Nov 2020

Use of Flavin-Containing Monooxygenases for Conversion of Trimethylamine in Salmon Protein Hydrolysates

Posted on: 24 Nov 2020

Metabolomics analysis of microbiota-gut-brain axis in neurodegenerative and psychiatric diseases

Posted on: 21 Nov 2020

A body weight loss- and health-promoting gut microbiota is established after bariatric surgery in individuals with severe obesity

Posted on: 06 Nov 2020

Protocol 20: Untargeted Metabolomics Determination of Postmortem Changes in Brain Tissue Samples by UHPLC-ESI-QTOF-MS and GC-EI-Q-MS

Posted on: 01 Nov 2020

Protocol 16: GC-MS Nontargeted Metabolomics of Neural Tissue

Posted on: 01 Nov 2020

Insulin Resistance in Obese Children: What Can Metabolomics and Adipokine Modelling Contribute?

Posted on: 29 Oct 2020

Capillary electrophoresis-Mass spectrometry at Trial by Metabo-ring: Effective electrophoretic mobility for Reproducible and Robust Compound Annotation

Posted on: 22 Sep 2020

Unraveling the Cyclization of l-Argininosuccinic Acid in Biological Samples: A Study via Mass Spectrometry and NMR Spectroscopy

Posted on: 21 Ago 2020

Exploring novel systemic biomarker approaches in grass‐pollen sublingual immunotherapy using omics

Posted on: 19 Ago 2020

Plasma metabolomic fingerprint of advanced cirrhosis stages among HIV/HCV‐coinfected and HCV‐monoinfected patients

Posted on: 27 Jun 2020

Dysregulation of glycerophospholipid metabolism during Behçet’s disease contributes to a pro-inflammatory phenotype of circulating monocytes

Posted on: 11 May 2020

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

Posted on: 08 May 2020

Plasma Metabolic Signature of Atherosclerosis Progression and Colchicine Treatment in Rabbits

Posted on: 27 Abr 2020

Data-dependent normalization strategies for untargeted metabolomics – a case study

Posted on: 14 Abr 2020

Comprehensive Examination of the Mouse Lung Metabolome Following Mycobacterium Tuberculosis Infection Using a Multiplatform Mass Spectrometry Approach

Posted on: 14 Abr 2020

Metabolic changes during respiratory syncytial virus infection of epithelial cells

Posted on: 26 Mar 2020

Metabolite annotation using in-silico generated compounds: MINE and BioTransformer

Posted on: 19 Mar 2020

Metabolite annotation with CEU Mass Mediator

Posted on: 19 Mar 2020

Unveiling the Fragmentation Mechanisms of Modified Amino Acids as the Key for Their Targeted Identification

Posted on: 02 Mar 2020

Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice

Posted on: 06 Feb 2020

Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis

Posted on: 16 Dic 2019

Metabolomic profile of BALB/c macrophages infected with Leishmania amazonensis: Deciphering L-arginine metabolism

Posted on: 11 Dic 2019

Functional microbiome deficits associated with ageing: Chronological age threshold

Posted on: 15 Nov 2019

FGF21-protection against fructose-induced lipid accretion and oxidative stress is influenced by maternal nutrition in male progeny

Posted on: 09 Nov 2019

Recent Developments along the Analytical Process for Metabolomics Workflows

Posted on: 18 Oct 2019

LAS: A Lipid Annotation Service Capable of Explaining the Annotations It Generates

Posted on: 30 Jul 2019

Insulin receptor substrate 2 (IRS2) deficiency delays liver fibrosis associated with cholestatic injury

Posted on: 16 Jul 2019

Oxidized glycerophosphatidylcholines in diabetes through non-targeted metabolomics: Their annotation and biological meaning

Posted on: 01 Jul 2019

Capillary electrophoresis mass spectrometry as a tool for untargeted metabolomics

Posted on: 23 May 2019

Metabolomics Reveals Altered Postprandial Lipid Metabolism after a High-Carbohydrate Meal in Men at High Genetic Risk of Diabetes

Posted on: 02 May 2019

The type 2 diabetes susceptibility PROX1 gene variants are associated with postprandial plasma metabolites profile in non-diabetic men

Posted on: 19 Abr 2019

Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping

Posted on: 06 Mar 2019

Metabolomics reveals citric acid secretion in mechanically–stimulated osteocytes is inhibited by high glucose

Posted on: 19 Feb 2019

Metabolomic and glycomic findings in posttraumatic stress disorder

Posted on: 10 Ene 2019

Metabolomic Study of Hibernating Syrian Hamster Brains: In Search of Neuroprotective Agents

Posted on: 09 Ene 2019

Bioprospecting Reveals Class III ω-Transaminases Converting Bulky Ketones and Environmentally Relevant Polyamines

Posted on: 09 Ene 2019

CEU Mass Mediator 3.0: A Metabolite Annotation Tool

Posted on: 21 Dic 2018

Characterization and annotation of oxidized glycerophosphocholines for non-targeted metabolomics with LC-QTOF-MS data

Posted on: 11 Dic 2018

Molecular basis of the leishmanicidal activity of the antidepressant Sertraline as a drug repurposing candidate

Posted on: 26 Nov 2018

In-and-out molecular changes linked to the type 2 diabetes remission after bariatric surgery: An influence of gut microbes on mitochondria metabolism

Posted on: 24 Nov 2018

Metabolomics analysis of leishmania by capillary electrophoresis and mass spectrometry

Posted on: 13 Nov 2018

Differential Effects of a Glucagon-Like Peptide 1 Receptor Agonist in Non-Alcoholic Fatty Liver Disease and in Response to Hepatectomy

Posted on: 07 Nov 2018

Flow Cytometry Has a Significant Impact on the Cellular Metabolome

Posted on: 26 Oct 2018

Metabolic Phenotyping Using Capillary Electrophoresis Mass Spectrometry

Posted on: 12 Oct 2018

Untargeted metabolomics: an overview of its usefulness and future potential in prenatal diagnosis

Posted on: 04 Oct 2018

Metabolomics changes in patients with PAPP-A2 deficiency in response to rhIGF1 treatment

Posted on: 12 Ago 2018

Multi-omics analysis points to altered platelet functions in severe food-associated respiratory allergy

Posted on: 20 Jul 2018

CE-MS for Metabolomics: A Comparison with Other Techniques

Posted on: 13 Jul 2018


Posted on: 09 Jul 2018

Effects of HIV, antiretroviral therapy and prebiotics on the active fraction of the gut microbiota

Posted on: 19 Jun 2018

A review of validated biomarkers obtained through metabolomics

Posted on: 06 Jun 2018

Knowledge-based metabolite annotation tool: CEU Mass Mediator

Posted on: 30 May 2018

Interplay between gut microbiota metabolism and inflammation in HIV infection

Posted on: 23 May 2018

Target and untargeted GC–MS based metabolomic study of mouse optic nerve and its potential in the study of neurological visual diseases

Posted on: 10 May 2018

Ferritin H deficiency in myeloid compartments dysregulates host energy metabolism and increases susceptibility to Mycobacterium tuberculosis infection

Posted on: 03 May 2018

Complex interplay between sphingolipid and sterol metabolism revealed by perturbations to the leishmania metabolome caused by miltefosine

Posted on: 26 Abr 2018

Metabolic Clustering Analysis as a Strategy for Compound Selection in the Drug Discovery Pipeline for Leishmaniasis

Posted on: 19 Abr 2018

Metabolomic-Based Methods in Diagnosis and Monitoring Infection Progression

Posted on: 07 Abr 2018

Short overview on metabolomic approach and redox changes in psychiatric disorders

Posted on: 05 Abr 2018

Transcription factor NRF2 as a therapeutic target for chronic diseases: A systems medicine approach

Posted on: 05 Abr 2018

Short overview on metabolomics approach to study pathophysiology of oxidative stress in cancer

Posted on: 01 Abr 2018

“Gear mechanism” of bariatric interventions revealed by untargeted metabolomics

Posted on: 20 Mar 2018

Stereochemical and structural effects of (2R,6R)-hydroxynorketamine on the mitochondrial metabolome in PC-12 cells

Posted on: 09 Mar 2018

Multiplatform plasma fingerprinting in cancer cachexia: a pilot observational and translational study

Posted on: 20 Feb 2018

Quality assurance procedures for mass spectrometry untargeted metabolomics. A review

Posted on: 05 Ene 2018

GC–MS based Gestational Diabetes Mellitus longitudinal study: Identification of 2-and 3-hydroxybutyrate as potential prognostic biomarkers

Posted on: 10 Sep 2017

Metabolic and evolutionary patterns in the extremely acidophilic archaeon Ferroplasma acidiphilum YT

Posted on: 16 Jun 2017

Antibiotic use and microbiome function

Posted on: 15 Jun 2017

Phenotyping of gut microbiota: Focus on capillary electrophoresis

Posted on: 12 Jun 2017

Metabolomics allows the discrimination of the pathophysiological relevance of hyperinsulinism in obese prepubertal children

Posted on: 07 Jun 2017

A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema

Posted on: 30 May 2017

A review of blood sample handling and pre-processing for metabolomics studies

Posted on: 19 May 2017

Differentiating signals to make biological sense – A guide through databases for MS-based non-targeted metabolomics

Posted on: 20 Abr 2017

Metabolomics and neuroanatomical evaluation of post-mortem changes in the hippocampus

Posted on: 11 Mar 2017

Exploring the human microbiome from multiple perspectives: Factors altering its composition and function

Posted on: 25 Feb 2017

Allergic asthma: an overview of metabolomic strategies leading to the identification of biomarkers in the field

Posted on: 04 Feb 2017

Metabolomic fingerprinting in the comprehensive study of liver changes associated with onion supplementation in hypercholesterolemic Wistar rats

Posted on: 28 Ene 2017

Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice

Posted on: 03 Ene 2017

The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects

Posted on: 21 Dic 2016

Capillary electrophoresis mass spectrometry as a tool for untargeted metabolomics

Posted on: 06 Dic 2016

A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice

Posted on: 23 Nov 2016

Projects by Coral Barbas:

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